Evidence map›Paper›PMID 41282510›Full record

ArticleBiomedical reports2026

Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature.

Yutaro Fukuma, Mitsuaki Ishida, Emi Yasuda, Kensuke Nakanishi, Shuhei Kushiyama, Atsushi Tomioka, Mitsuhiro Asakuma, Yoshinobu Hirose

Abstract readCase Reports
In one paragraph

Article in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yutaro FukumaDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Mitsuaki IshidaDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Emi YasudaDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Kensuke NakanishiDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Shuhei KushiyamaDepartment of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Atsushi TomiokaDepartment of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Mitsuhiro AsakumaDepartment of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
Yoshinobu HiroseDepartment of Pathology, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterotopic ossification (HO) is the formation of mature bone tissues in non-skeletal tissues and has been reported in various types of neoplasms. The presence of HO in pancreatic tumors is rare, with only 16 cases reported in the English literature, and the mechanism of HO formation remains unclear. In the present study, the 17th to 19th cases of HO in pancreatic neoplasms were described and the literature on HO in pancreatic neoplasms was reviewed. Three Japanese women with pancreatic masses on imaging underwent laparoscopic distal pancreatectomy. The three pancreatic masses were histopathologically diagnosed as a pancreatic neuroendocrine tumor (NET), mucinous cystic neoplasm (MCN), and intraductal papillary mucinous neoplasm, and HO was found in all of them. Neither pancreatic NET with HO nor MCN with HO has yet been reported in the English-language literature, and to our knowledge, these are the first such reports. Although rare, the knowledge that various types of pancreatic tumors, including NETs and MCNs, are associated with HO may be useful in daily practice, and the significance of tumor-associated HO is discussed.

Indexed as

HOIPMNMCNpancreatic neoplasmpancreatic NET

Identifiers

PMID41282510
PMCPMC12635607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.