ArticleRegenerative therapy2025
The research landscape and trends of dental pulp stem cell studies (2010-2025): A bibliometric analysis.
Article in Regenerative therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bibliometric and science-mapping analysis of translation-oriented signals across six dental stem-cell subtypes: a Web of Science study (2000-2025).Oral and maxillofacial surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dental pulp stem cells (DPSCs) have emerged as a promising therapeutic modality in regenerative medicine, yet systematic bibliometric evaluation of global research landscape has been lacking. Methods: Publications from 2010 to 2025 were retrieved from Web of Science Core Collection. After screening, 4599 English-language articles and reviews were analyzed using VOSviewer, CiteSpace, and Bibliometrix for publication trends, geographic distribution, author collaboration, journal characteristics, citation networks, and keyword co-occurrence. Results: Global DPSC research demonstrated sustained growth, with annual publications increasing from 97 in 2010 to 464 in 2024. China (32.6 %), United States (15.9 %), and Japan (9.9 %) contributed over half the global output, though U.S. publications achieved higher citation impact. Sichuan University, Sun Yat-sen University, and Capital Medical University ranked highest in productivity. Author collaboration revealed interconnected clusters led by pioneering researchers including Shi Songtao, Nakashima Misako, and Nor Jacques E. Journal of Endodontics was the leading publishing platform, while co-citation analysis highlighted intellectual influence of multidisciplinary journals including Stem Cells, Biomaterials, and PNAS. Keyword analyses demonstrated thematic evolution from cellular characterization toward translational applications, with emerging frontiers focusing on extracellular vesicles, exosomes, and cell-free therapeutic strategies. Conclusions: DPSC research has evolved into a mature, internationally collaborative scientific discipline successfully bridging fundamental biology and clinical application. A pivotal paradigm shift from cell-centric to cell-free therapies is currently underway. Future breakthroughs will likely depend on harnessing the DPSC secretome and developing intelligent, clinically viable regenerative strategies.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.