Evidence map›Paper›PMID 41282272›Full record

ArticleJournal of oral biology and craniofacial research

The effect of

Syafrizal Aji Pamungkas, Chiquita Prahasanti, Sylvia Wardah, Devi Luciana Kusriawati, Maria Jessica Anggakusuma, Michael Ganda Wijaya, Michelle Suhartono, Wibi Riawan, Zulvikar Syambani Ulhaq

Abstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Syafrizal Aji PamungkasDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Chiquita PrahasantiDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Sylvia WardahDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Devi Luciana KusriawatiDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Maria Jessica AnggakusumaDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Michael Ganda WijayaDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Michelle SuhartonoDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia.
Wibi RiawanDepartment of Biochemistry, Faculty of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia.
Zulvikar Syambani UlhaqResearch Center for Pre-clinical and Clinical Medicine, National Research and Innovation Agency, Cibinong, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontitis is a chronic inflammatory disease initiated by polymicrobial infection, characterized by an imbalance between subgingival microbiota and host immune defense. This imbalance results in the destruction of tooth-supporting tissues, with Objective: To evaluate the impact of the probiotic Methods: Gingival tissue samples from a Results: In a rat model of periodontitis, probiotic supplementation suppressed inflammation by reducing TNF-α, IL-6, and IL-1β levels while increasing IL-10 expression in the gingival epithelium, thereby restoring the balance between pro- and anti-inflammatory mediators. Additionally, treatment accelerated wound healing, as indicated by upregulation of TGF-β1 and downregulation of MMP-8. Conclusion: Our study shows that

Indexed as

EMTInflammationPeriodontitisProbioticWound healing

Identifiers

PMID41282272
PMCPMC12630346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.