Evidence map›Paper›PMID 41282265›Full record

ArticleResearch square2025

How Sup35 monomer conformation and amyloid fibril polymorphism determine yeast strain phenotypes.

Motomasa Tanaka, Takashi Nomura, David Boyer, Yusuke Komi, Peng Ge, Rodrigo A Maillard, Piere Rodriguez, Atsushi Yamagata, Mikako Shirouzu, Giuseppe Legname and 2 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Motomasa TanakaRIKEN Center for Brain Science.ORCID 0000-0002-2994-7703
Takashi NomuraRIKEN Center for Brain Science.ORCID 0000-0002-4613-7403
David BoyerUniversity of California Los Angeles.ORCID 0000-0002-4487-0230
Yusuke KomiRIKEN Brain Science Institute.
Peng GeUniversity of California, Los Angeles.ORCID 0000-0002-2661-8226
Rodrigo A MaillardUniversity of California, Berkeley, QB3 Institute.
Piere RodriguezUniversity of California.ORCID 0000-0002-3828-4235
Atsushi YamagataRIKEN.ORCID 0000-0001-9285-1256
Mikako ShirouzuRIKEN.ORCID 0000-0002-7997-2149
Giuseppe LegnameScuola Internazionale Superiore di Studi Avanzati (SISSA).ORCID 0000-0003-0716-4393
Bruno SamoriUniversity of Bologna.
David EisenbergUCLA.ORCID 0000-0003-2432-5419

Funding

The Stanford-SLAC CryoEM CenterR24GM154186 · NIGMS · STANFORD UNIVERSITY · PI Wah Chiu, BRITT HEDMAN · 2024 to 2026
$19.3M
THE PHYSICAL CHEMISTRY OF NUCLEIC ACIDSR01GM032543 · NIGMS · UNIVERSITY OF OREGON · PI CARLOS Jose BUSTAMANTE · 1985 to 2026
$6.4M
Towards Treatment of Alzheimer’s Disease by Targeting Pathogenic Tau and Beta-Amyloid StructuresR01AG070895 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DAVID EISENBERG · 2022 to 2026
$5.8M
Development of inhibitors and diagnostics for amyloid diseasesRF1AG048120 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EISENBERG, DAVID · 2019 to 2019
$1.9M
NIA NIH HHS R01 AG070895NIA NIH HHS RF1 AG048120NIGMS NIH HHS R01 GM032543NIGMS NIH HHS R24 GM154186
6 · The paper itself

Abstract

In the [

Identifiers

PMID41282265
PMCPMC12637829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.