Evidence map›Paper›PMID 41282253›Full record

ArticleResearch square2025

Structure of the giant RNA polymerase ejected from coliphage N4.

Nathan F Bellis, Ravi K Lokareddy, Mikhail Pavlenok, Stephanie L Cooper Horton, James L Kizziah, Francesca Forti, David A Schneider, Michael Niederweis, Federica Briani, Gino Cingolani

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nathan F BellisDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1825 University Blvd, Birmingham, AL 35294, USA.
Ravi K LokareddyDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1825 University Blvd, Birmingham, AL 35294, USA.
Mikhail PavlenokDepartment of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA.
Stephanie L Cooper HortonDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1825 University Blvd, Birmingham, AL 35294, USA.ORCID 0000-0001-9928-002X
James L KizziahInstitutional Research Core Program (IRCP), University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA.ORCID 0000-0002-2608-8595
Francesca FortiDipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy.
David A SchneiderDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1825 University Blvd, Birmingham, AL 35294, USA.ORCID 0000-0003-0635-5091
Michael NiederweisDepartment of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA.ORCID 0000-0003-4068-8092
Federica BrianiDipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0002-5876-4463
Gino CingolaniDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, 1825 University Blvd, Birmingham, AL 35294, USA.ORCID 0000-0002-9206-9640

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8M
Toxin secretion and trafficking by Mycobacterium tuberculosisR01AI175106 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MICHAEL NIEDERWEIS · 2023 to 2026
$3.0M
Mechanism of Viral Genome Delivery into CellsR35GM140733 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CINGOLANI, GINO · 2021 to 2025
$2.8M
UNDERSTANDING THE ROLES OF RNA POLYMERASE I IN TRANSCRIPTION AND BEYONDR35GM140710 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SCHNEIDER, DAVID ALAN · 2021 to 2025
$2.1M
Acquisition of cryo-electron microscopeS10OD024978 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DOKLAND, TERJE · 2020 to 2020
$2.0M
Molecular investigation of siderophore secretion and drug efflux by Mycobacterium tuberculosisR01AI184596 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MICHAEL NIEDERWEIS · 2025 to 2026
$1.5M
Mechanisms of STAT1 and STAT3 canonical and persistent activation in physiology and diseaseR01AI191107 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Gino Cingolani · 2025 to 2026
$1.3M
NCI NIH HHS 75N91019D00024NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI175106NIAID NIH HHS R01 AI184596NIAID NIH HHS R01 AI191107NIGMS NIH HHS R35 GM140710NIGMS NIH HHS R35 GM140733NIGMS NIH HHS U24 GM129541NIH HHS S10 OD024978
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41282253
PMCPMC12633501

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.