Evidence map›Paper›PMID 41282193›Full record

ArticleResearch square2025

PIP

Jianmin Cui, Lu Zhao, Xianjin Xu, Chenxi Cui, Rui Duan, Ali Kermani, Jingyi Shi, Lu Han, Ji Sun, Xiaoqin Zou

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    PIP2026
5 · Who and what money

Authors and funding

10 authors.

Jianmin CuiWashington University in Saint Louis.ORCID 0000-0002-9198-6332
Lu ZhaoWashington University in St. Louis.ORCID 0000-0003-3533-7693
Xianjin XuUniversity of Missouri - Columbia.
Chenxi CuiNational University of Singapore.ORCID 0000-0001-9698-4494
Rui DuanUniversity of Missouri.
Ali KermaniSt Jude Children's Research Hospital.
Jingyi ShiWashington University in St. Louis.
Lu HanWashington University in Saint Louis.
Ji SunSt Jude Children's Rsearch Hospital.ORCID 0000-0002-9302-3177
Xiaoqin ZouUniversity of Missouri-Columbia.ORCID 0000-0003-0637-8648

Funding

Structure prediction and in silico screening of protein-peptide interactionsR35GM136409 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI XIAOQIN ZOU · 2020 to 2026
$2.9M
A full spectrum rational approach to identify antiarrhythmic agents targeting IKs ChannelsR01HL166628 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Jianmin Cui, RICHARD Z LIN · 2023 to 2026
$2.8M
Gating Mechanisms of KCNQ1/IKS ChannelsR01HL155398 · NHLBI · WASHINGTON UNIVERSITY · PI CUI, JIANMIN · 2021 to 2024
$2.5M
Structural and Pharmacological Study of the KCNQ1/KCNE1 Potassium Channel ComplexR00HL143037 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUN, JI · 2020 to 2022
$747k
NHLBI NIH HHS R00 HL143037NHLBI NIH HHS R01 HL155398NHLBI NIH HHS R01 HL166628NIGMS NIH HHS R35 GM136409
6 · The paper itself

Abstract

The I

Indexed as

anti-arrhythmia therapyC-PIP2IKsKCNQ1V-PIP2

Identifiers

PMID41282193
PMCPMC12633489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.