ArticleResearch square2025
Suicide risk genes impact evolutionarily conserved survival strategies.
Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Genome-wide association studies (GWAS) and candidate gene analyses have identified possible suicide risk genes that are highly conserved during evolution and enriched in genes essential for life. However, functional roles for these risk genes have not been confirmed and pathways from risk variant to relevant phenotype to suicidality-related behavior remain unknown, highlighting critical gaps in our knowledge. Here, we report findings from the largest behavioral and mechanistic study of suicide risk genes to date. In
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