Evidence map›Paper›PMID 41282066›Full record

ArticleResearch square2025

The influence of bilingualism on the assessment and treatment of an Italian-English speaker with the logopenic variant of PPA.

Roberta Tomasoni, Gaia C Santi, Serena Tagliente, Chiara Griseta, Simona Aresta, Allegra Benzini, Paola Santacesaria, Cinzia Palmirotta, Maria Luisa Mandelli, Stephanie Grasso and 1 more

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In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Roberta TomasoniIstituti Clinici Scientifici Maugeri IRCCS Bari.
Gaia C SantiIstituti Clinici Scientifici Maugeri IRCCS Bari.
Serena TaglienteIstituti Clinici Scientifici Maugeri IRCCS Bari.
Chiara GrisetaIstituti Clinici Scientifici Maugeri IRCCS Bari.
Simona ArestaIstituti Clinici Scientifici Maugeri IRCCS Bari.
Allegra BenziniIstituti Clinici Scientifici Maugeri IRCCS Bari.
Paola SantacesariaIstituti Clinici Scientifici Maugeri IRCCS Bari.
Cinzia PalmirottaIstituti Clinici Scientifici Maugeri IRCCS Bari.
Maria Luisa MandelliMemory and Aging Center, University of California San Francisco, San Francisco, California, USA.
Stephanie GrassoDepartment of Speech, Language and Hearing Sciences, University of Texas at Austin, Austin, TX, USA.
Petronilla BattistaIstituti Clinici Scientifici Maugeri IRCCS Bari.

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Primary Progressive Aphasia: Cognition, Anatomy and ProgressionRF1NS050915 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORNO TEMPINI, MARIA LUISA · 2022 to 2022
$4.7M
Word fluency task performance as a marker of Alzheimer’s disease in Tagalog/English bilingual speakerR01AG080396 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jessica Anne Deleon · 2023 to 2026
$3.3M
Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive AphasiaR01AG080470 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI Stephanie M Grasso · 2023 to 2026
$2.8M
NIA NIH HHS P01 AG019724NIA NIH HHS R01 AG080396NIA NIH HHS R01 AG080470NINDS NIH HHS RF1 NS050915
6 · The paper itself

Abstract

introductionThe impact of bilingualism on speech-language assessment and therapy in Primary Progressive Aphasia (PPA) remains underexplored, despite its suggested influence on disease presentation.

methodsA bilingual Italian (L1)-English (L2) individual with logopenic-variant PPA completed a bilingual assessment and dual-language Lexical Retrieval Therapy. His bilingual experience was characterized, and therapy outcomes were evaluated within and across languages.

resultsPre-morbidly, the patient was a relatively balanced bilingual with stronger L1 literacy. Following disease onset, L2 showed faster decline, while L1 remained stable. Age of acquisition, dominance, and language use were among the main factors contributing to language maintenance and decline. Therapy yielded equivalent item-specific gains in both languages (L1 d DISCUSSION: Findings support the relevance of in-depth bilingual assessment and therapy underpinning successful treatment in PPA, unveiling the significance of bilingual experience in shaping treatment outcomes.

Indexed as

bilingual experiencebilingual speech-language assessmentbilingual speech-language interventioncross-linguistic transferlexical retrieval therapymultilingualismPrimary progressive aphasia

Identifiers

PMID41282066
PMCPMC12633202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.