Evidence map›Paper›PMID 41282040›Full record

ReviewMedical archives (Sarajevo, Bosnia and Herzegovina)2025

Impact of Areca Catechu Kombucha on Inflammatory Markers and Gut Microbiota - a Review.

Dina Aprillia Ariestine, Dina Keumala Sari, Lambok Siahaan, Tri Widyawati, Muhammad Rusda, Masitha Dewi Sari, Sri Sofyani, Mustafa Mahmud Amin

Abstract readReview
In one paragraph

Review in Medical archives (Sarajevo, Bosnia and Herzegovina), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dina Aprillia AriestineFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Dina Keumala SariFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Lambok SiahaanFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Tri WidyawatiFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Muhammad RusdaFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Masitha Dewi SariFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Sri SofyaniFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Mustafa Mahmud AminFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding the aging process has become one of the global concerns as the world faces the new challenges of an aging population. Central to this phenomenon is cellular senescence, marked by an irreversible growth arrest due to cellular damage. Gut microbiome is a dynamic community of microorganisms influenced by diet, environmental exposures, and aging. Objective: This research highlights the significant impact of gut microbiota composition on overall health, particularly in older adults, where deterioration in microbial diversity can lead to adverse health outcomes. Kombucha, a fermented tea beverage, has emerged as a potential gut microbiota modulator, offering antioxidant properties and digestive support. Specifically, Kombucha derived from Areca catechu shows promise in modulating inflammatory markers and gut microbiota composition. Methods: This review synthesizes current literature on the relationship between aging, frailty, and gut health, with a particular focus on gut microbiota composition and chronic inflammation, referred to as "inflammaging." We specifically investigate the potential of Kombucha, a fermented tea beverage, to modulate gut microbiota and inflammatory markers. Results: Kombucha, a fermented tea beverage, has emerged as a potential gut microbiota modulator, offering antioxidant properties and digestive support. Specifically, Kombucha derived from Areca catechu shows promise in modulating inflammatory markers and gut microbiota composition. This review synthesizes current literature on the interplay between aging, frailty, and gut health-focusing on the role of gut microbiota and chronic inflammation ("inflammaging")-to elucidate the therapeutic potential of Kombucha in promoting gut health and mitigating age-related decline, thereby contributing to a deeper understanding of its role in the aging process. Discussion: This research elucidates the therapeutic potential of Kombucha in promoting gut health and mitigating age-related decline, contributing to a deeper understanding of its role in the aging process. The interplay between gut microbiota and chronic inflammation highlights the importance of dietary interventions in managing health in aging populations. Conclusion: Kombucha presents a viable strategy for modulating gut health and addressing the challenges of aging, emphasizing the need for further exploration of its benefits in older adults.

Indexed as

AgingGastrointestinal MicrobiomeInflammationKombucha TeaAntioxidantsBiomarkersHumansAntioxidantsBiomarkersKombucha TeaElderlyInflammatory MarkerKombuchaMicrobiota

Identifiers

PMID41282040
PMCPMC12634076

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.