Evidence map›Paper›PMID 41282028›Full record

ArticleFrontiers in medicine2025

Ethnic and sex differences in corneal nerves and corneal epithelial cells in healthy population.

Fengyi Liu, Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Hassan Mansoor, Ching-Yu Cheng, Wajid Ali Khan, Jodhbir S Mehta, Yu-Chi Liu

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fengyi LiuSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Chang LiuRegenerative Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.
Mingyi YuRegenerative Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.
Isabelle Xin Yu LeeRegenerative Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.
Hassan MansoorAl-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.
Ching-Yu ChengOphthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Singapore.
Wajid Ali KhanAl-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.
Jodhbir S MehtaRegenerative Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.
Yu-Chi LiuRegenerative Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aim to investigate the ethnic and sex differences in corneal nerves and epithelial cell metrics among healthy Chinese and Indian populations. Methods: This cross-sectional study included 15,850 corneal nerve and 9,510 corneal epithelial cell images from 328 individuals, categorized into Chinese and Indian ethnicities. Results: There were 208 Chinese participants (101 males, 107 females) in this study with a mean age of 57.0 ± 15.6 years, and 120 Indian participants (58 males, 62 females) with a mean age of 55.8 ± 21.2 years ( Conclusion: Our study identifies significant ethnic and sex disparities in corneal nerves and epithelium. These should be considered when evaluating corneal metrics in Chinese and Indian populations.

Indexed as

corneal epithelial cellcorneal nerveethnicityin-vivo confocal microscopysex

Identifiers

PMID41282028
PMCPMC12634647

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.