Evidence map›Paper›PMID 41281954›Full record

ArticleWellcome open research2025

Transmission dynamics for invasive Non-Typhoidal

Peter I Johnston, Kenneth Chizani, Esmeda Chirwa, Helen Dale, Pyianka Patel, Niza Silungwe, Chifundo Mkwangwanya, Tamando Kachala, Chipiliro Mhango, Grace Nyirenda and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Virulence and antimicrobial resistance inFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Peter I JohnstonClinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.ORCID https://orcid.org/0000-0001-9400-6339
Kenneth ChizaniMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Esmeda ChirwaClinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.
Helen DaleClinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.ORCID https://orcid.org/0000-0002-4171-1226
Pyianka PatelMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Niza SilungweMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Chifundo MkwangwanyaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Tamando KachalaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Chipiliro MhangoMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Grace NyirendaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Yohane DinessMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Star MpesiMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Richard WachepaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Florence ShumbaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Felistas MwakiseghileMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Vincent RashidMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Theresa MisiriMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Philip M AshtonClinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.
Angeziwa ChungaMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.
Derek CockerClinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.ORCID https://orcid.org/0000-0002-6670-2713
Edward Cunningham-OakesDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, England, UK.ORCID https://orcid.org/0000-0003-0260-5508
Chris JewellSchool of Mathematical Sciences, Lancaster University, Lancaster, LA1 4YF, UK.ORCID https://orcid.org/0000-0002-7902-2178
Nicholas FeaseyMalawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.ORCID https://orcid.org/0000-0003-4041-1405
Melita A Gordon *Clinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection Veterinary and Ecological Sciences, Neston, England, UK.
Tonney Nyirenda *Malawi Liverpool Wellcome Clinical Research Programme, Blantyre, Malawi.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Invasive non-typhoidal Methods: We will recruit all members of at least 60 households in Ndirande, Blantyre, Malawi. Stool samples will be collected every other day for at least four weeks and tested for NTS using culture and pan- Conclusions: TiNTS will define the burden, transmission patterns, and immune response to eNTS. Findings will inform vaccine modelling, trial design, and targeted introduction strategies.

Indexed as

antimicrobial resistance (AMR)Environmental reservoirsgenomicslongitudinal cohort studymetagenomicsNon-typhoidal Salmonella (NTS)transmissionUrban informal settlement

Identifiers

PMID41281954
PMCPMC12635526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.