Evidence map›Paper›PMID 41281944›Full record

ArticleCancer drug resistance (Alhambra, Calif.)2025

RCC1 knockdown sensitizes drug-resistant colorectal cancer to 5-fluorouracil or doxorubicin by impairing DNA repair.

Jing Li, Ya Meng, Xumei Ouyang, Xiaowen Lin, Yangzhe Wu, Hang Fai Kwok

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer drug resistance (Alhambra, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing LiCancer Centre, Faculty of Health Sciences, University of Macau, Macau 999078, China.
Ya MengGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (ZhuHai Clinical Medical College of Jinan University), Zhuhai 519099, Guangdong, China.
Xumei OuyangGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (ZhuHai Clinical Medical College of Jinan University), Zhuhai 519099, Guangdong, China.
Xiaowen LinGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (ZhuHai Clinical Medical College of Jinan University), Zhuhai 519099, Guangdong, China.
Yangzhe WuGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (ZhuHai Clinical Medical College of Jinan University), Zhuhai 519099, Guangdong, China.
Hang Fai KwokCancer Centre, Faculty of Health Sciences, University of Macau, Macau 999078, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-fluorouracilchemoresistancecolorectal cancerDNA damage responsedoxorubicinRCC1

Identifiers

PMID41281944
PMCPMC12635986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.