ArticleLaryngoscope investigative otolaryngology2025
Predictive Value of Blood Eosinophil Ratio for Risk Stratification in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Predictive value of blood eosinophil count and serum total immunoglobulin E for type 2 chronic rhinosinusitis according to allergic sensitization status.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- CRSwNP in the biologics era: evaluating patient-reported quality of life outcomes.Frontiers in allergy · 2026Review
- Predictive Value of Blood Eosinophil Ratio for Risk Stratification in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps.Laryngoscope investigative otolaryngology · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP) is associated with severe symptoms and poor outcomes, but the diagnostic criteria remain elusive. The objective of this study is to identify preoperative predictors of ECRSwNP using multiple diagnostic thresholds and to propose a clinically actionable risk stratification model. Methods: A retrospective analysis was conducted on 1081 CRSwNP patients who underwent endoscopic sinus surgery. Receiver operating characteristic (ROC) curves were generated to predict ECRSwNP based on clinical features and identify reliable predictors. Results: Both the blood eosinophil count and ratio were identified as indicators for predicting ECRSwNP. The ratio exhibited the strongest correlation with that of tissue ( Conclusion: Blood eosinophil ratio ≥ 3.25% identifies CRSwNP patients at high risk for eosinophilic inflammation, providing a preoperative stratification tool. While correlations between blood and tissue eosinophils were moderate, this threshold balances sensitivity and specificity across heterogeneous diagnostic criteria.
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