Evidence map›Paper›PMID 41281638›Full record

ReviewMaterials today. Bio2025

Mechanisms, optimization strategies, and applications of highly sensitive piezoelectric nanomaterials in tumor therapy.

Haohao Zhang, Mingyuan Pang, Juan An, Min Yang, Zhen Kong, Linzheng Ren, Zifan Wang, Jiajia Ye, Yen Leng Pak, Xing Gao and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haohao ZhangCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Mingyuan PangCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Juan AnCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Min YangCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Zhen KongCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Linzheng RenSchool of Computer and Information Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Zifan WangCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Jiajia YeCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Yen Leng PakCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Xing GaoCollege of Chemical and Biological Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Jibin SongCollege of Chemistry, Beijing University of Chemical Technology, Beijing, 10010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piezocatalytic therapy based on ultrasound stimulation is an emerging tumor treatment technology. The ultrasound-activated piezoelectric effect can induce reactions of molecules in the surrounding environment, generating reactive oxygen species with strong oxidizing properties, which trigger cell apoptosis or activate the immune system to enhance the body's anti-tumor immune response. However, existing conventional piezocatalytic materials suffer from limitations such as functional restrictions and poor catalytic efficiency, failing to achieve efficient piezocatalytic therapy. Therefore, the development of piezocatalytic nanomaterials with high sensitivity and synergistic multiple therapeutic mechanisms is urgently needed. Against this backdrop, this paper provides a detailed introduction to the catalytic mechanisms of piezocatalytic materials, material modification strategies for enhancing piezocatalytic sensitivity and efficiency, as well as their application effects in clinical fields including tumor treatment and wound healing. Finally, this paper also discusses the current challenges and future directions for the further development of piezocatalytic materials and their applications.

Indexed as

PerovskitesPiezoelectric catalyticReactive oxygen speciesSemiconductorsSonodynamic therapyTumor therapy

Identifiers

PMID41281638
PMCPMC12639900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.