Evidence map›Paper›PMID 41281546›Full record

ArticleFrontiers in neurology2025

Familial prevalence of psoriasis in patients with multiple sclerosis - results from an Australian survey.

Varitsara Mangkorntongsakul, Ariadna Fontes-Villalba, Chun-Ting Justin Kwong, Olivia Charlton, Helen Marie McGuire, Turlough Montague, Kevin Phan, Venkatesha Venkatesha, Geoffrey Herkes, Saxon Smith and 1 more

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Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Varitsara MangkorntongsakulFaculty of Medicine and Health, Northern Clinical School, The University of Sydney, Darlington, NSW, Australia.
Ariadna Fontes-VillalbaFaculty of Medicine and Health, Northern Clinical School, The University of Sydney, Darlington, NSW, Australia.
Chun-Ting Justin KwongFaculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Darlington, NSW, Australia.
Olivia CharltonDepartment of Dermatology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Helen Marie McGuireFaculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Darlington, NSW, Australia.
Turlough MontagueDepartment of Neurology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Kevin PhanDepartment of Dermatology, Liverpool Hospital, NSW, Australia.
Venkatesha VenkateshaNorthern Sydney Local Health District Executive, Royal North Shore Hospita, St. Leonards, NSW, Australia.
Geoffrey HerkesFaculty of Medicine and Health, Northern Clinical School, The University of Sydney, Darlington, NSW, Australia.
Saxon SmithFaculty of Medicine and Health, Northern Clinical School, The University of Sydney, Darlington, NSW, Australia.
John ParrattFaculty of Medicine and Health, Northern Clinical School, The University of Sydney, Darlington, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The familial association of psoriasis with multiple sclerosis (MS) has been observed in several international studies. Whether this link is applicable in an Australian setting has yet to be established. The aim of this study was to evaluate the prevalence of psoriasis in family members of an MS cohort in the Australian population. Methods: A survey study of adult MS patients was conducted between 2018 and 2021 at the MS clinic, Royal North Shore Hospital, Sydney, Australia. Results: A total of 204 MS participants, with mean age of 48.8 years, were included in the study. Of these participants, 67 were male (32.8%) and 137 were female (67.2%). An increased rate of psoriasis was found among family members of MS patients: 35 (17.2%) MS patients had family history of psoriasis, and 11 patients reported a history of psoriasis themselves. Of the 35 MS patients with family history of psoriasis, female participants were found to be at a higher risk of psoriasis (34.6%, Discussion: This study demonstrates a significantly increased risk of psoriasis among family members of MS patients, suggesting overlap in genetic risk between the two immune-mediated diseases. Further prospective research is warranted to determine the characteristics of association in MS individuals with psoriasis or/and family history of psoriasis.

Indexed as

Australian populationautoimmune diseasefamilial studymultiple scleroisneuroimmunologypsoriasissurvey study

Identifiers

PMID41281546
PMCPMC12631082

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