Evidence map›Paper›PMID 41281541›Full record

ArticleWorld journal of psychiatry2025

Association between childhood maltreatment with subthreshold depressive symptoms and major depressive disorder in young and middle-aged adults.

Jing-Man Shi, Yu-Hua Liao, Yan-Zhi Li, Gia Han Le, Roger S McIntyre, Wei-Hong Zhang, Ines Keygnaert, Wan-Xin Wang, Lan Guo, Hui-Min Zhang and 4 more

Abstract read
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In one paragraph

Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jing-Man ShiDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Yu-Hua LiaoDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, Guangdong Province, China.
Yan-Zhi LiDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Gia Han LeInstitute of Medical Science, University of Toronto, Toronto M5S 3H2, Canada.
Roger S McIntyreDepartment of Pharmacology and Toxicology, University of Toronto, Toronto M5S 3H2, Canada.
Wei-Hong ZhangInternational Centre for Reproductive Health (ICRH), Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent 9000, Belgium.
Ines KeygnaertInternational Centre for Reproductive Health (ICRH), Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent 9000, Belgium.
Wan-Xin WangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Lan GuoDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Hui-Min ZhangDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, Guangdong Province, China.
Cai-Hong GaoDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, Guangdong Province, China.
Yan ChenDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, Guangdong Province, China.
Xue HanDepartment of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen 518054, Guangdong Province, China.
Ci-Yong LuDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China. luciyong@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildhood maltreatment has a potentially lasting influence on subthreshold depressive symptoms (SDS) and major depressive disorder (MDD). This study aimed to explore the association of childhood maltreatment with MDD and SDS, focusing on the differences between young and middle-aged adults.

aimTo examine the associations among childhood maltreatment, SDS, and MDD in young and middle-aged adults.

methodsA total of 3209 adults were recruited from 34 primary healthcare settings. The Childhood Trauma Questionnaire-28 item Short Form was used to assess childhood maltreatment. The Patient Health Questionnaire-9 was used to assess SDS and the Mini-International Neuropsychiatric Interview depression module was used to assess MDD.

resultsChildhood maltreatment was significantly associated with higher odds of developing SDS and MDD than in the non-depressed control group (

conclusionOur study revealed a strong association among childhood maltreatment, SDS, and MDD across age groups, highlighting the impact of emotional abuse and need for trauma-informed depression care.

Indexed as

AdultsChildhood maltreatmentMajor depressive disorderSubthreshold depressive symptoms

Identifiers

PMID41281541
PMCPMC12635630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.