Evidence map›Paper›PMID 41281520›Full record

ArticleWorld journal of psychiatry2025

Efficacy of electroacupuncture for cervical spondylosis-related pain in patients with generalized anxiety disorder.

Zhe Li, Yu Gao, Dong Yan, Yi-Hui Feng

Abstract read
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Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhe LiDepartment of Pain Disease Treatment, Zhengzhou Orthopaedic Hospital, Zhengzhou 450052, Henan Province, China.
Yu GaoDepartment of Cervicolumbar, Zhengzhou Orthopaedic Hospital, Zhengzhou 450052, Henan Province, China.
Dong YanDepartment of Cervicolumbar, Zhengzhou Orthopaedic Hospital, Zhengzhou 450052, Henan Province, China.
Yi-Hui FengDepartment of Acupuncture and Moxibustion, University of Health and Rehabilitation Sciences, Qingdao 266042, Shandong Province, China. walgzzh@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical spondylosis (CS) frequently co-occurs with generalized anxiety disorder (GAD), presenting a complex clinical challenge. Managing CS-related pain in patients with GAD is particularly challenging because of the bidirectional relationship between pain and anxiety, necessitating integrated treatment strategies.

aimTo evaluate the efficacy of electroacupuncture (EA) in treating CS-related pain and anxiety in patients with GAD.

methodsThis retrospective cohort study analyzed data from 83 patients with CS-related pain and GAD who received EA treatment over 2-year period. Pain intensity was assessed using the visual analog scale, and anxiety symptoms were measured using the Hamilton Anxiety Rating Scale. Additionally, neuroinflammatory markers, including interleukin-6, tumor necrosis factor-alpha, and high-sensitivity C-reactive protein, were examined. Outcomes were evaluated at baseline, after 4 weeks, and after 8 weeks of treatment.

resultsEA treatment significantly reduced CS-related pain (mean visual analog scale reduction: 3.24 ± 1.18;

conclusionEA demonstrates significant efficacy in reducing CS-related pain in patients with comorbid GAD, along with concurrent improvements in anxiety symptoms and neuroinflammatory profiles. These findings suggest that EA may offer a valuable integrative approach for managing this complex clinical presentation, potentially addressing both pain and anxiety through the modulation of neuroinflammatory pathways.

Indexed as

Cervical spondylosisElectroacupunctureGeneralized anxiety disorderNeuroinflammationPain management

Identifiers

PMID41281520
PMCPMC12635652

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