ArticleMedComm2025
Impaired Cellular Immunity and Cross-Reactive Humoral Responses to Mpox Virus in HIV-Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain.
Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Dose-dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus.Animal models and experimental medicine · 2026Article
- Article
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Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the global response to the current mpox epidemic, understanding immune memory to the vaccinia virus and cross-immunity to the mpox virus (MPXV) among people living with HIV (PLWH) is critical. Blood samples were collected from PLWH born between 1949 and 2002 without MPXV infection, as well as from sex- and age-matched healthy donors (HD). Note that 62% and 56% of vaccinated PLWH born before 1980 had antibodies against the vaccinia virus Tiantan (VTT) strain and MPXV, respectively, though these seropositivity rates were lower than in HD (84% vs. 80%). Neutralizing antibodies were detected in 9% of PLWH, compared to 32% in HD. Notably, in PLWH with CD4 T-cell counts below 500 cells/mm
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