ArticleHealth science reports2025
From Fat to Healing: How Adipose-Derived Stem Cells Are Changing the Game for Diabetic Foot Ulcers-A Perspective.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Advancing fat graft survival: from adipose-derived stem cell mechanisms to next-generation regenerative strategies.Frontiers in cell and developmental biology · 2026Review
- From Fat to Healing: How Adipose-Derived Stem Cells Are Changing the Game for Diabetic Foot Ulcers-A Perspective.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aim: Diabetic foot ulcers (DFUs) pose a significant challenge in the management of chronic wounds, characterized by a high risk of infection and severe complications, including potential limb amputation. The limitations of conventional treatments have sparked interest in regenerative therapies, particularly the use of adipose-derived stem cells (ADSCs). which possess significant potential across various medical fields for enhancing tissue repair and modulating immune responses. This perspective critically evaluates the potential of ADSCs for treating DFUs while exploring their broader implications in regenerative medicine. Methods: This perspective incorporates insights from a comprehensive literature review, with searches conducted on platforms such as Google Scholar, PubMed, and Scopus. The selected studies focus on the regenerative efficacy, safety, and clinical applications of ADSCs in wound healing, emphasizing rigorous methodologies that support reliable conclusions. Results: ADSCs exhibit significant promise in promoting tissue regeneration, stimulating angiogenesis, and modulating immune function-mechanisms that are beneficial not only for patients with DFUs but also for those with other chronic and non-healing wounds. Nevertheless, challenges persist, including the risk of tumorigenesis, particularly in patients with a history of cancer, as well as variability in therapeutic outcomes due to donor characteristics and processing techniques. Conclusion: While ADSCs represent a promising therapeutic option for DFUs and provide valuable insights for a wider array of chronic wound therapies, their clinical application requires careful consideration of safety concerns, including risks of tumor formation and immune response issues. Future advancements in cell processing and well-structured clinical trials will be essential to ensuring efficacy across diverse populations in the broader context of regenerative medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.