Evidence map›Paper›PMID 41281162›Full record

ArticleHealth science reports2025

Evaluation of Hypertension in Pediatric Hemolytic Uremic Syndrome (A Cross-Sectional Study).

Mahdi Banaei Nourmohammadi, Fahimeh Askarian, Arash Abbasi, Behnaz Bazargani, Daryoush Fahimi, Mastaneh Moghtaderi

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahdi Banaei NourmohammadiTehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0009-0002-8795-2073
Fahimeh AskarianPediatric Chronic Kidney Diseases Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-8199-4996
Arash AbbasiPediatric Chronic Kidney Diseases Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-0008-2937
Behnaz BazarganiPediatric Chronic Kidney Diseases Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0001-8938-7376
Daryoush FahimiPediatric Chronic Kidney Diseases Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-8950-2124
Mastaneh MoghtaderiPediatric Chronic Kidney Diseases Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0001-6862-4504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemolytic uremic syndrome (HUS), particularly the Shiga toxin-producing Objectives: This study is designed to determine the prevalence of HTN among children diagnosed with HUS and to identify its potential clinical correlates, including laboratory parameters and cardiac involvement. Methods: A descriptive cross-sectional study was conducted on 50 pediatric patients diagnosed with HUS and hospitalized in our tertiary nephrology ward between 2021 and 2024. Clinical and laboratory data, including blood pressure, BMI, renal function markers, and echocardiographic findings, were extracted from medical records. HTN was defined using the AAP Pediatric HTN calculator. Statistical analysis was performed using SPSS v26 software, t-tests, chi-square, and Fisher's exact test. Results: HTN was observed in 48% of our patients. No significant associations were found between HTN and age, sex, BMI, HUS type, urea, creatinine, or hemoglobin levels. However, HTN was significantly associated with hypokalemia ( Conclusion: Although this study is a small one and was done in a single center, it supports the importance of HTN in patients with HUS. HTN is quite prevalent among children with HUS and shows a significant association with cardiac complications and electrolyte imbalances. These findings indicate the importance of routine blood pressure monitoring and cardiovascular assessment in the management of pediatric HUS. Lifelong follow-up is recommended for early detection of signs of chronic kidney and cardiovascular sequelae.

Indexed as

acute kidney injuryE. colihemolytic uremic syndromehypertensionpediatric

Identifiers

PMID41281162
PMCPMC12630544

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.