Evidence map›Paper›PMID 41281153›Full record

ArticleCureus2025

Efficacy of Thoracic Duct Embolization in Managing Severe Refractory Chyle Leak Post-cervical Reconstruction in a Patient With Liver Cirrhosis: A Case Report.

Masato Nagaoka, Hirokazu Ashida, Nobuki Fukuda, Katsuhiro Ishida, Hiromi Kojima

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Masato NagaokaDepartment of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, JPN.
Hirokazu AshidaDepartment of Radiology, Jikei University School of Medicine, Tokyo, JPN.
Nobuki FukudaDepartment of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, JPN.
Katsuhiro IshidaDepartment of Plastic and Reconstructive Surgery, Jikei University School of Medicine, Tokyo, JPN.
Hiromi KojimaDepartment of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a patient with a history of liver cirrhosis who underwent neck reconstruction surgery and subsequently experienced substantial chyle leakage, reaching volumes of up to 6,620 mL per day. Conservative interventions such as fasting, a low-fat diet, total parenteral nutrition, drainage management, somatostatin analogs, and factor XIII supplementation proved ineffective, and the patient exhibited a refractory treatment course. The pronounced chyle leakage in this instance was hypothesized to be linked to increased lymph production resulting from portal hypertension associated with liver cirrhosis. Given the resistance to conservative treatment, thoracic duct embolization was performed by the interventional radiology department, effectively controlling the chyle leakage. The patient experienced a favorable clinical trajectory, devoid of complications. These findings indicate that thoracic duct embolization is a safe and efficacious minimally invasive treatment for refractory and massive chyle leakage following neck dissection and may represent a promising alternative before surgical intervention.

Indexed as

chylous leakconservative treatmentliver cirrhosisneck dissectionthoracic duct embolization

Identifiers

PMID41281153
PMCPMC12631710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.