Evidence map›Paper›PMID 41281090›Full record

ArticleCureus2025

Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor in a Young Woman With Congenital HIV.

Mariam Hafez, Ahmed Ebeid, Alisa Dewald, Abdelrhman Refaey, Reid Schalet, Mamoun Younes, Ameer Abutaleb

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariam HafezTransplant Hepatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Ahmed EbeidInternal Medicine Department, Howard University Hospital, Washington, DC, USA.
Alisa DewaldTransplant Hepatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Abdelrhman RefaeyInternal Medicine, Holy Name Medical Center, Teaneck, USA.
Reid SchaletInternal Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Mamoun YounesDepartment of Pathology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Ameer AbutalebTransplant Hepatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare condition involving smooth muscle tumors in various organs, often in the context of immunodeficiency. Hepatic EBV-SMT usually presents with non-specific symptoms such as abdominal pain and weight loss. We present a case of a 25-year-old woman who presented with multiple liver masses in the setting of congenital human immunodeficiency virus (HIV). Initially, those lesions were suspected to represent metastatic tumors, but the biopsy showed smooth muscle proliferation suggestive of a smooth muscle tumor. Diagnosis of EBV-SMT was confirmed through in situ hybridization for EBV RNA. This case underscores the diagnostic challenges and pathogenesis of EBV-SMT.

Indexed as

biopsycongenital immunodeficiencyepstein-barr virusleiomyomasmooth muscle tumor

Identifiers

PMID41281090
PMCPMC12631944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.