Evidence map›Paper›PMID 41281020›Full record

ArticleCureus2025

Secondary Neuropathy From Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Case Report.

Peter Young, Maxwell Kroloff

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter YoungInternal Medicine/General Internal Medicine and Health Services Research, University of California, Los Angeles, Los Angeles, USA.
Maxwell KroloffOncology, University of California, Los Angeles, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 62-year-old woman who presented with signs and symptoms of distal sensory polyneuropathy. Her initial electromyography and nerve conduction studies (EMG/NCS) showed a severe length-dependent neuropathy with uniform demyelination and secondary axonal changes. After extensive evaluation for secondary causes, she was ultimately found to have polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. She underwent treatment with lenalidomide and dexamethasone, followed by an autologous stem cell transplant, and is now doing well with marked improvement in her function. This case emphasizes the importance of evaluating for secondary causes of polyneuropathy and provides a brief overview of POEMS syndrome.

Indexed as

acquired neuropathydistal symmetric polyneuropathyperipheral neuropathyplasma cell disorderpoems polyneuropathypoems syndromepolyneuropathysecondary neuropathy

Identifiers

PMID41281020
PMCPMC12635500

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.