ArticleACS omega2025
Development of an Electrochemical Immunosensor for Detecting Coagulation Factor Xa and Perspectives in Monitoring Direct Oral Anticoagulant Therapy.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Electrochemical Detection of SMN Protein by Immunosensors: The Role of Surface Modifications in Screen-Printed Carbon Electrodes.Sensors (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to develop a point-of-care (POC) electrochemical immunosensor to monitor the anticoagulant activity of direct oral anticoagulants (DOACs) by detecting and distinguishing between the inactive (FX) and active (FXa) forms of Factor X. DOACs have transformed the management of thromboembolic disorders by selectively inhibiting FXa. Common monitoring methods are either insufficiently sensitive to DOAC levels or not widely accessible. This study demonstrates the development of a graphene-based electrochemical immunosensor modified by gold nanostructures and functionalized with anti-FX antibodies. Electrode modifications were characterized by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and field-emission scanning electron microscopy (FESEM), showing enhanced electron transfer and increased current peaks (
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Registered trials
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