Evidence map›Paper›PMID 41280804›Full record

ArticleACS omega2025

Device-Free Nucleic Acid Detection Enabled by Body Temperature-Assisted DEMBA.

Jianying Yi, Li Wan, Jia Ding, Qing Ye, Hong Mu, Guoyue Yang, Lingling Lu, Chunlei Zhou

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianying YiDepartment of Clinical Laboratory, Tianjin First Central Hospital, Tianjin 300192, China.
Li WanThe School of Medicine, Nankai University, Tianjin 300071, China.
Jia DingDepartment of Intensive Care Unit, Ningbo NO.2 Hospital, Ningbo, Zhejiang 315010, China.
Qing YeKey Laboratory of Weak-Light Nonlinear Photonics, Ministry of Education, School of Physics and TEDA Applied Physics, Nankai University, Tianjin 300071, China.ORCID https://orcid.org/0000-0002-1203-6540
Hong MuDepartment of Clinical Laboratory, Tianjin First Central Hospital, Tianjin 300192, China.
Guoyue YangDepartment of Medical Services, Central Hospital, Tianjin University / Tianjin Third Central Hospital, Tianjin 300170, China.ORCID https://orcid.org/0009-0002-8578-1645
Lingling LuThe School of Medicine, Nankai University, Tianjin 300071, China.
Chunlei ZhouDepartment of Clinical Laboratory, Tianjin First Central Hospital, Tianjin 300192, China.ORCID https://orcid.org/0009-0000-9242-3091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a novel nucleic acid detection method, the body temperature endonuclease-dependent molecular beacon assay (DEMBA). In DEMBA, the fluorescence signal is significantly lower in the absence of the target sequence compared to its presence, demonstrating the assay's responsiveness. This study utilized two DEMBA probes incorporating restriction endonucleases (

Identifiers

PMID41280804
PMCPMC12631429

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.