Evidence map›Paper›PMID 41280754›Full record

ArticleACS omega2025

Effect of a Low Electrostatic Environment on the Helical Structures of Peptides and Proteins Using Flexible Water Models: An In Silico Study.

Jorge Alberto Aguilar-Pineda, Jesús Pérez-Aguilar, Minerva González-Melchor

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jorge Alberto Aguilar-PinedaInstituto de Física "Luis Rivera Terrazas", Benemérita Universidad Autónoma de Puebla, Av San Claudio, Cd Universitaria, Apdo. Postal J-48, Puebla 72570, Mexico.ORCID https://orcid.org/0000-0003-2921-5681
Jesús Pérez-AguilarInstituto de Física "Luis Rivera Terrazas", Benemérita Universidad Autónoma de Puebla, Av San Claudio, Cd Universitaria, Apdo. Postal J-48, Puebla 72570, Mexico.
Minerva González-MelchorInstituto de Física "Luis Rivera Terrazas", Benemérita Universidad Autónoma de Puebla, Av San Claudio, Cd Universitaria, Apdo. Postal J-48, Puebla 72570, Mexico.ORCID https://orcid.org/0000-0002-8975-3740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The electrostatic representation of the molecular environment surrounding membrane proteins is a topic that has not been addressed in the field of molecular simulations. The forces produced by such environments play a decisive role in processes such as GPCR activation, molecular recognition between membrane components, and interactions with ligands, directly impacting their dynamics and physiological function. Based on the FBA/ϵ and TIP4P/ϵ

Identifiers

PMID41280754
PMCPMC12631355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.