Population responses in V1 encodes stimulus visibility in backward masking.

Itiel Dennis, Hadar Edelman-Klapper, Gal Gadi Raveh, Osnat Bar-Shira, Shany Nivinsky Margalit, Hamutal Slovin

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In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Itiel DennisThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Hadar Edelman-KlapperThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Gal Gadi RavehThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Osnat Bar-ShiraThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Shany Nivinsky MargalitThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Hamutal SlovinThe Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat Gan, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The visibility of a briefly presented stimulus is diminished when followed by a mask, a phenomenon known as backward masking (BM). As the interval between the stimulus and the mask (stimulus-to-mask onset asynchrony [SOA]) becomes shorter, the stimulus visibility decreases. Yet, the neural mechanism underlying BM remains poorly understood. To investigate this, monkeys were trained to discriminate oriented targets in a pattern BM paradigm. Using voltage-sensitive dye imaging, we measured the population responses in the primary visual cortex (V1). The behavioral performance in short SOAs was lower, and reaction times were slower. Population response in V1 showed a figure-ground modulation (FGm) with lower values for short SOAs. A classification analysis revealed the differences in temporal dynamics of the model accuracy in relation to stimulus visibility and spatial rearrangements of the informative neural patterns. These results suggest that the mask interferes with FGm in V1, possibly leading to diminished stimulus visibility.

Indexed as

Biological sciencesNatural sciencesNeuroscienceSensory neuroscience

Identifiers

PMID41280689

DOI10.1016/j.isci.2025.113814

PMCPMC12637068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.