ArticleJournal of family medicine and primary care2025
Causality, severity, seriousness, and preventability of adverse drug reactions: A retrospective analysis.
Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of chatbot interventions in individuals for hypertension management: a systematic review and narrative synthesis.Frontiers in digital health · 2026Pooled it
- Analysis of adverse drug reactions reported at a teaching hospital in 2023-24.Journal of postgraduate medicine · 2026Observational
- Characteristics, preventability, management, and predictors of adverse drug reaction-related hospital admissions: a cross-sectional study in a Thai tertiary care hospital.Journal of pharmaceutical policy and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adverse drug reactions (ADRs) are a significant cause of preventable morbidity and mortality. They account for 10-20% of hospital admissions and have a high economic impact on healthcare infrastructure. This study aims to provide information about the pattern, causality, severity, seriousness, and preventability of an ADR reported during the study period. Material and Methods: This was an observational, rétrospective, record-based study to analyze all submitted spontaneous Individual Case Safety Reports (ICSRs) during three years (April 2020-March 2023) at the ADR monitoring center under PvPI. Data obtained from ICSRs were carefully evaluated for quality, based on their essential elements. The ADR outcome was categorized into recovered, recovering, not recovered upon discharge, fatal, and unknown. The information in the ICSRs was used to assess the causality, preventability, severity, and seriousness of the ADRs. Results: Out of 380 Individual Case Safety Reports (ICSRs) from April 2020 to March 2023, 313 fully completed ICSRs were analyzed. The number of adverse drug reactions was higher in males ( Conclusion: Adverse drug reactions (ADRs) are a global problem and a major concern for patient safety. Monitoring and reporting ADRs is crucial to reduce their incidence and enhance pharmacovigilance. There is a need to increase awareness among patients, clinicians, and staff members about reporting and preventing ADRs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.