Evidence map›Paper›PMID 41280556›Full record

ArticleThe Lancet regional health. Europe2026

Percutaneous and surgical management of aortic stenosis in the SWEDEHEART registry (2013-2023): a nationwide observational study.

Johannes Tödt, Sasha Koul, Troels Yndigegn, Oskar Angerås, Henrik Bjursten, Shahab Nozohoor, Örjan Friberg, Jenny Backes, Stefan James, Björn Redfors and 6 more

Abstract read
In one paragraph

Article in The Lancet regional health. Europe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Johannes TödtDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Sasha KoulDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Troels YndigegnDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Oskar AngeråsDepartment of Thoracic Surgery and Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Henrik BjurstenDepartment of Cardiothoracic Surgery, Anesthesia and Intensive Care, Lund University/Skåne University Hospital, Lund, Sweden.
Shahab NozohoorDepartment of Cardiothoracic Surgery, Anesthesia and Intensive Care, Lund University/Skåne University Hospital, Lund, Sweden.
Örjan FribergSchool of Medica Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Jenny BackesDepartment of Cardiothoracic Surgery, Anesthesia and Intensive Care, Lund University/Skåne University Hospital, Lund, Sweden.
Stefan JamesDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Björn RedforsDepartment of Thoracic Surgery and Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Patrik GiljeDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Ashkan LabafDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Henrik HagströmDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Andreas RückDivision of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Matthias GötbergDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Moman Aladdin MohammadDivision of Cardiology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Management of severe aortic stenosis (AS) has evolved over the past decade, driven by the widespread adoption of transcatheter aortic valve implantation (TAVI). This study aims to assess trends in procedural volumes, patient characteristics, and outcomes for patients undergoing TAVI or surgical aortic valve replacement (SAVR) in Sweden. Methods: This was a descriptive, non-comparative, nationwide cohort study using the SWEDEHEART registry. We included 21,383 patients who underwent TAVI or SAVR between 2013 and 2023 (11,366 TAVI and 10,017 SAVR). Trends in patient characteristics, preoperative risk, complications and mortality were examined. Findings: TAVI procedures increased from 307 (26.1%, n = 307/1174) in 2013 to 1851 (71.2%, n = 1851/2601) in 2023, while SAVR volumes declined from ∼1000 annually before 2018 to roughly 750 procedures annually. Median age of TAVI patients were 81 (IQR 77, 85) years and 71 (IQR 65, 76) years for SAVR patients. The median EuroSCORE II for TAVI decreased from 5.6 (IQR 3.3, 10.2) to 2.7 (IQR 1.7, 4.6) (p = 0.002), and STS-PROM from 3.3 (IQR 1.9, 4.1) to 1.6 (IQR 1.1, 2.8) (p = 0.0021). Among SAVR patients, EuroSCORE II decreased from 1.5 (IQR 1.0, 2.3) to 1.3 (IQR 0.9, 2.1) (p = 0.022) and STS-PROM from 1.8 (IQR 1.2, 3.0) to 1.6 (IQR 1.1, 2.6) (p = 0.0082). Any in-hospital complications declined significantly for TAVI (29.2%, n = 210/719 to 13.2%, n = 244/1851), while SAVR complication rates increased slightly (18.4%, n = 354/1921 to 18.7%, n = 140/750). In-hospital mortality for TAVI declined from 3.6% (n = 26/719) to 1.0% (n = 18/1851), and 1-year mortality from 11.1% to 6.9% (p = 0.019). SAVR in-hospital all-cause death decreased from 1.6% to 0.4% (n = 3/750) and 5.0% to 2.2% for 1-year mortality (p = 0.013). Interpretation: TAVI has become the predominant treatment strategy for AS in Sweden expanding access within the treated cohort. Despite this, current 2023 SAVR results demonstrate similar in-hospital complication rates compared to TAVI (18.7% vs 13.2%), but lower in-hospital (0.4% vs 1.0%) and 1-year mortality rates (2.2% vs 6.9%). Funding: This study was supported by ALF and national research funding bodies.

Indexed as

Aortic stenosisAortic valve implantationProsthetic aortic valve implantationSCSRSurgical aortic valve replacement (SAVR)SWEDEHEARTSWENTRYTemporal trendsTranscatheter aortic valve implantation (TAVI)Valve replacement outcomes

Identifiers

PMID41280556
PMCPMC12630323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.