ArticleHeart rhythm O22025
Long-term low-voltage impedance measurements in subcutaneous implantable cardioverter-defibrillators.
Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: High-voltage impedance (HVI), measured during subcutaneous implantable cardioverter-defibrillator (S-ICD) implantation via defibrillation testing or a synchronized shock, is associated with defibrillation efficacy. Recently, S-ICD systems have been upgraded to automatically perform long-term measurements of low-voltage impedance (LVI) using a 1-V subthreshold pulse. Objective: This study evaluated LVI as a surrogate for HVI and described its long-term trends in S-ICD recipients. Methods: We analyzed data from 1226 patients who underwent de novo S-ICD implantation across 15 Italian centers. Weekly averages of LVI and HVI were calculated, and agreement between simultaneous measurements was assessed. Results: Over a median follow-up of 37 months (interquartile range 20-57 months), 373 paired HVI and LVI measurements were analyzed. LVI strongly correlated with HVI ( Conclusion: LVI showed strong agreement with HVI during follow-up, supporting its potential use as a noninvasive surrogate for HVI. LVI increased during the initial postimplantation period and subsequently stabilized, possibly reflecting physiological changes.
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