Evidence map›Paper›PMID 41280536›Full record

ArticleHeart rhythm O22025

In-hospital complications of hybrid vs endocardial atrial fibrillation ablation.

Mahmoud Eisa, Nauman Naeem, Hossam Elbenawi, Asmaa Ahmed, Andrew Takla, Amir Hanafi, Abhishek J Deshmukh, Christopher V DeSimone, Mohan Rao

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Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahmoud EisaDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York.
Nauman NaeemDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York.
Hossam ElbenawiDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Asmaa AhmedDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York.
Andrew TaklaDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York.
Amir HanafiDepartment of Internal Medicine, Unity Hospital, Rochester, New York.
Abhishek J DeshmukhDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Christopher V DeSimoneDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Mohan RaoSands Constellation Heart Institute, Rochester Regional Health, Rochester, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hybrid atrial fibrillation (AF) ablation has been used to achieve rhythm control in AF management. It requires both epicardial and endocardial ablation. There is limited evidence regarding the safety of this procedure. Objective: The study aimed to compare in-hospital complication rates between hybrid AF ablation and endocardial catheter ablation (ECA) using a nationally representative dataset. Methods: Using the National Inpatient Sample, we identified patients who underwent AF ablation between 2017 and 2022. The cohort was divided into 2 groups; those who underwent ECA and those who underwent hybrid AF ablation. The primary outcome was major adverse cardiovascular events (MACEs). Results: After propensity score weighting, hybrid ablation was associated with a significantly lower MACE rate (3.1% vs 5.6%, Conclusion: Hybrid AF ablation was associated with a significantly lower MACE rate compared with ECA, contrasting with earlier studies that suggested higher risk. This shift likely reflects improvements in technique and more refined patient selection. While rates of pulmonary and hemorrhagic complications were higher with hybrid ablation, transfusion needs remained similar between groups.

Indexed as

Atrial fibrillationEndocardial ablationHybrid ablationMACENIS databasePropensity score weighting

Identifiers

PMID41280536
PMCPMC12635746

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.