ArticleHeart rhythm O22025
Assessment of physicians' adherence to guideline-directed medical therapy among patients with heart failure with reduced ejection fraction at the University of Gondar Comprehensive Specialized Hospital, Northwest, Ethiopia, 2023.
Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Assessment of prescriber adherence to guideline-directed medical therapy for heart failure at Jimma Medical Center, Ethiopia.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adhering well to guideline-directed medical therapy (GDMT) is essential for improving treatment outcomes in patients with heart failure (HF) with reduced ejection fraction (HFrEF). Despite its significance, studies on the status of GDMT adherence in patients with HF in Ethiopia are scarce. Objective: This study aimed to assess physicians' adherence to GDMT and the associated factors in patients with HFrEF. Methods: A retrospective follow-up study was conducted from September 1, 2018, to July 31, 2023. Quality of Adherence to Guideline Recommendations for Lifesaving Treatment in Heart Failure Survey scores were used to assess physicians' adherence to GDMT. SPSS version 27.0 was used for analysis, and multinomial logistic regression analysis was performed. Results: The Quality of Adherence to Guideline Recommendations for Lifesaving Treatment in Heart Failure Survey scores showed that the physicians' adherence to GDMT was good in 40% (95% confidence interval [CI] 35.30-44.90), moderate in 33.8% (95% CI 29.3-38.6), and poor in 26.2% of the study participants (95% CI 22-30.7). Age of ≥65 years (adjusted odds ratio [AOR] 0.14, 95% CI 0.07-0.29); causes of HF such as ischemic heart disease (AOR 16, 95% CI 6.75-37.90), valvular heart disease (AOR 5.3, 95% CI 2.58-10.92), dilated cardiomyopathy (AOR 8.24, 95% CI 3.97-17.09), and hypertension (AOR 6.62, 95% CI 2.98-14.69); and duration of HFrEF of ≥3 years (AOR 2.59, 95% CI 1.32-5.08) were factors significantly associated with good physicians' adherence to GDMT. Conclusion: The use of all indicated medications as per the guideline recommendation for HFrEF was low, and most patients received suboptimal doses of GDMT. Particularly, the beta-blocker dose was very suboptimal. Encouraging healthcare provider training, access to separate cardiac clinics and cardiologists, following guidelines, timely patient appointments, and medication availability are recommended for better clinical outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.