Evidence map›Paper›PMID 41280406›Full record

ArticlePhotoacoustics2025

In-bore MRI-compatible transrectal ultrasound and photoacoustic imaging.

Ryo Murakami, Yang Wang, Wojciech G Lesniak, Ryosuke Tsumura, Yichuan Tang, Shang Gao, Yasuyuki Tsunoi, Christopher J Nycz, Martin G Pomper, Gregory S Fischer and 1 more

Abstract read
In one paragraph

Article in Photoacoustics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Ryo MurakamiRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Yang WangRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Wojciech G LesniakDepartment of Radiology, University of Texas Southwestern Medical Center, TX, United States.
Ryosuke TsumuraBiomedical Engineering, Worcester Polytechnic Institute, MA, United States.
Yichuan TangRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Shang GaoRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Yasuyuki TsunoiDivision of Bioinformation and Therapeutic Systems, National Defense Medical College Research Institute, Saitama, Japan.
Christopher J NyczRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Martin G PomperDepartment of Radiology, University of Texas Southwestern Medical Center, TX, United States.
Gregory S FischerRobotics Engineering, Worcester Polytechnic Institute, MA, United States.
Haichong K ZhangRobotics Engineering, Worcester Polytechnic Institute, MA, United States.

Funding

PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
Physician Assistance Technology in Image-guided Robotic Intervention of ProstateR01EB030539 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI HATA, NOBUHIKO, ZHANG, HAICHONG · 2021 to 2024
$2.7M
Automatic Wide-Field Optical Coherence Tomography for Assessment of Transplant Kidney ViabilityR01DK133717 · NIDDK · UNIVERSITY OF MASSACHUSETTS AMHERST · PI POTTER, STEVEN, TANG, QINGGONG · 2022 to 2025
$2.5M
Robotic Lung Ultrasound for Triage of COVID-19 Patients in a Resource-Limited EnvironmentDP5OD028162 · OD · WORCESTER POLYTECHNIC INSTITUTE · PI ZHANG, HAICHONG · 2019 to 2023
$2.3M
NCI NIH HHS R01 CA134675NIBIB NIH HHS R01 EB030539NIDDK NIH HHS R01 DK133717NIH HHS DP5 OD028162
6 · The paper itself

Abstract

Prostate cancer (PCa) remains one of the leading causes of cancer-related mortality in males. While MRI is widely used for PCa diagnosis due to its high sensitivity, it is limited by its poor specificity in detecting aggressive PCa. Molecular targeted photoacoustic (PA) imaging is a non-ionizing technique known for its potential to achieve both high sensitivity and specificity. It also provides real-time imaging capability, which complements MRI's limitation of slow imaging speed during intraoperative image-guided procedures. This research presents a tri-modal imaging system that integrates MRI, PA, and ultrasound (US) to enhance PCa diagnosis and image-guided procedures. We introduce an MRI-compatible PA/US imaging platform featuring a reflector-based transrectal probe with an integrated optical fiber delivery channel. The probe's MRI-compatible actuation system enables 3D PA/US imaging in parallel with MRI scanning. Comprehensive performance evaluation included phantom studies to assess imaging quality, MRI compatibility, and

Indexed as

MRI-compatibleMRI-compatible roboticsProstate cancerThree-dimensional imagingTransrectalTri-modal imaging

Identifiers

PMID41280406
PMCPMC12637062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.