Evidence map›Paper›PMID 41280388›Full record

SynthesisFrontiers in nutrition2025

The biological relationship among depression, vitamins B

Rosella Soriano-Gonzalez, Hugo Ramirez-Olea, Rocio Gonzalez-Soltero, Rocio Alejandra Chavez-Santoscoy

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rosella Soriano-GonzalezTecnologico de Monterrey, School of Medicine and Health Sciences, Monterrey, Mexico.
Hugo Ramirez-OleaTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
Rocio Gonzalez-SolteroFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
Rocio Alejandra Chavez-SantoscoyTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Depression is a leading cause of disability worldwide; studies have described it as a multifactorial disease that involves biological, psychological, and environmental factors. This systematic review explores the role of vitamins B Methods: A systematic literature review was conducted in Web of Science (WOS) and PubMed up to 15th June 2025. This review included 24 studies from randomized controlled trials (RCTs), observational studies, and case reports and examined the associations between genetic variants involved in vitamins B Results: Studies varied widely in design and methodology. Deficiencies in vitamins B Conclusion: This systematic review emphasizes the role of vitamins B

Indexed as

depressionfolategenetic variantsMTHFRnutrigeneticsvitamin B12vitamin D

Identifiers

PMID41280388
PMCPMC12634520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.