Evidence map›Paper›PMID 41280383›Full record

ArticleFrontiers in nutrition2025

Increased BMI favors weaning in patients with chronic intestinal failure due to short bowel syndrome: a retrospective cohort study in Italy.

Fabio Dario Merlo, Palle Bekker Jeppesen, Umberto Aimasso, Fabio Bioletto, Marta Ossola, Valentina Ponzo, Ilaria Goitre, Marta Palermo, Elisa Olimpio, Stefano Silveri and 1 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Fabio Dario MerloClinical Nutrition Unit, "Città della Salute e della Scienza Hospital", Torino, Italy.
Palle Bekker JeppesenDepartment of Intestinal Failure and Liver Diseases, Rigshospitalet & Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Umberto AimassoClinical Nutrition Unit, "Città della Salute e della Scienza Hospital", Torino, Italy.
Fabio BiolettoDepartment of Medical Sciences, University of Torino, Torino, Italy.
Marta OssolaClinical Nutrition Unit, "Città della Salute e della Scienza Hospital", Torino, Italy.
Valentina PonzoDepartment of Medical Sciences, University of Torino, Torino, Italy.
Ilaria GoitreDepartment of Medical Sciences, University of Torino, Torino, Italy.
Marta PalermoDepartment of Medical Sciences, University of Torino, Torino, Italy.
Elisa OlimpioDepartment of Medical Sciences, University of Torino, Torino, Italy.
Stefano SilveriDepartment of Medical Sciences, University of Torino, Torino, Italy.
Simona BoClinical Nutrition Unit, "Città della Salute e della Scienza Hospital", Torino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A great heterogeneity exists among patients with chronic intestinal failure even with the same intestinal circuit. Weaning from parenteral support depends on intestinal adaptation, remnant bowel length, and functional capacity. The present study aimed to assess if pre-existent nutritional reserves would predict the possibility of enteral autonomy. Methods: This retrospective observational study evaluated the incidence of weaning off parenteral support in adult patients with chronic intestinal failure due to short bowel syndrome from an Italian referral center. Multivariable models, considering mortality as a competing risk, identified predictors of weaning. Results: Out of 251 patients, 116 (46.2%) died without being weaned and 76 (30.3%) were weaned off. The latter showed increased residual small bowel length, more frequently the colon-in-continuity and the ileocecal valve, lower age, higher weight and BMI (25.3 ± 5.6 Conclusion: Patients with chronic intestinal failure due to short bowel syndrome with increased BMI and a healthier body composition were more likely to be weaned off parenteral nutrition.

Indexed as

body compositionbody mass indexchronic intestinal failureparenteral nutritionshort bowel syndrome

Identifiers

PMID41280383
PMCPMC12631374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.