ArticleFrontiers in aging neuroscience2025
A trajectory study of postoperative frailty and cognitive function in elderly spinal surgery patients: a cohort study in China.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To explore the developmental trajectory of postoperative frailty and cognitive function in elderly spinal surgery patients and the predictive relationship between the two. Methods: A total of 266 elderly individuals were selected as the study subjects, and their debilitation and cognitive functions were tracked and investigated at T1 (at the time of discharge from the hospital), T2 (at 3 months postoperatively), and T3 (at 6 months postoperatively), and the data were analyzed using cross-lagged model and latent variable growth model. Results: The latent variable growth model showed a decreasing trend in frailty (S = -0.197, Conclusion: Elderly spinal surgery patients showed a decreasing trend of postoperative frailty and an increasing trend of postoperative cognitive function, frailty and postoperative cognitive function at the initial level had a mutual predictive effect, the initial level of frailty was able to negatively predict the rate of development of their own and postoperative cognitive function, and the initial level of postoperative cognitive function was able to positively predict the rate of development of frailty.
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