Evidence map›Paper›PMID 41280306›Full record

ArticleRespiratory medicine case reports2025

Symptomatic pulmonary cement embolism following PMMA vertebroplasty: Clinical presentation and management.

Haytham Najjar, Hind Neiroukh, Layth J M Saada, Mohamad Thalji, Kataeb Doudin

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Article in Respiratory medicine case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Haytham NajjarInternal Medicine Department, Indiana University School of Medicine-muncie, Indiana, USA.
Hind NeiroukhAl-Quds University, Jerusalem, Palestine.
Layth J M SaadaAl-Quds University, Jerusalem, Palestine.
Mohamad ThaljiSurgery Department, Al-Mezan Speciality Hospital, Hebron, West bank, Palestine.
Kataeb DoudinInternal Medicine Department, Al-Mezan Speciality Hospital, Hebron, West bank, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vertebroplasty, a minimally invasive technique frequently used for spine stabilization and vertebral compression fractures, uses polymethylmethacrylate (PMMA) bone cement. Although usually benign, pulmonary cement embolism (PCE) is an uncommon but potentially dangerous consequence that arises when bone cement enters the pulmonary circulation through the vertebral venous system. Although the majority of PCE cases are underdiagnosed and asymptomatic, the incidence varies between 2.1 % and 26 % of vertebroplasty surgeries. To prevent incorrect diagnoses and needless treatments, early detection is essential. Case presentation: We present the case of a 71-year-old woman with a history of type 2 diabetes mellitus and hypertension. She underwent laminectomy at the L3/4 and L4/5 levels in addition to PMMA cement-augmented intrapedicular fixation because of her severe spinal stenosis, hypertrophic facet joints, and instability. Three days following surgery, the patient had severe respiratory symptoms, including tachypnea, tachycardia, hypoxemia, and dyspnea. Additional oxygen was required due to oxygen desaturation. Non-contrast chest CT confirmed the presence of multiple bilateral high-density branching opacities in the pulmonary arteries that were compatible with PMMA emboli. Conclusion: This example emphasizes how difficult it can be to diagnose symptomatic PCE after spinal instrumentation and how crucial it is to keep a high level of suspicion when patients arrive with unexplained respiratory symptoms after vertebroplasty. The preferred diagnostic method remains non-contrast chest CT, and the majority of symptomatic individuals can be conservatively treated with extra oxygen and anticoagulation when necessary.

Indexed as

Bone cementNon-thrombotic pulmonary embolismPolymethylmethacrylate (PMMA)Postoperative dyspneaPulmonary cement embolismVertebroplasty

Identifiers

PMID41280306
PMCPMC12639584

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