Evidence map›Paper›PMID 41280300›Full record

ArticleInfection prevention in practice2025

Carbapenem-Resistant

Yuying Pang, Yan Hu, Jiaoyang Zhu, Zhaoxia Liu, Youquan Zhou, Xiumei Yang, Yifan Peng, Min Zhao

Abstract read
In one paragraph

Article in Infection prevention in practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuying PangDepartment of Hospital Infection Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Yan HuDepartment of Gynecologic Oncology. Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Jiaoyang ZhuClinical Medicine. Department of Hospital Infection Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Zhaoxia LiuMedical Laboratory Science. Department of Hospital Infection Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Youquan ZhouMedical Laboratory Science. Department of Laboratory Medicine, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Xiumei YangNursing Department of Hospital Infection Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Yifan PengClinical Medicine Department of Hospital Infection Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.
Min ZhaoCenter of Cancer Prevention and Control, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, Kunming, Yunnan 650000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We describe an outbreak of carbapenem-resistant Methods: Between June and July 2023, a comprehensive epidemiological investigation was conducted, including environmental hygiene surveillance and targeted infection control interventions. These measures focused on patients with CRKP nosocomial infections in the ICU, and their effectiveness was systematically evaluated. Results: A total of 22 CRKP strains were identified in 14 patients(including one transferred from another hospital), with 13 nosocomial infections. Five patients had infections at multiple sites. The nosocomial infection rate was 8.1%, representing a statistically significant increase compared to the same period in previous years. Environmental surveillance detected CRKP contamination on the hands of two doctors (8.7% detection rate) and on various surfaces (8% detection rate), particularly shared equipment, bed unit surfaces, and sanitary ware. Following the implementation of control measures, the spread was effectively contained. Conclusions: Key factors contributing to transmission likely included delayed identification of infected patients, inadequate enforcement of isolation protocols, and suboptimal environmental cleaning and disinfection. Early detection, strict isolation measures, and thorough environmental cleaning are essential for effective prevention and control of CRKP in the ICU setting.

Indexed as

Carbapenem-resistant Klebsiella pneumoniaeIntensive care unitInvestigation and controlOutbreak

Identifiers

PMID41280300
PMCPMC12639431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.