Evidence map›Paper›PMID 41280278›Full record

ArticleSynthetic and systems biotechnology2026

Amplicon-based prediction of secondary metabolic potential of microbiomes facilitates natural product discovery.

Zhen-Yi Zhou, Qun-Jian Yin, Buddha Bahadur Basnet, Zi-Yang Li, Gen Li, Mahmoud Emam, Qi-Hao Wu, Hong Wang, Bin Wei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhen-Yi ZhouCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Qun-Jian YinFourth Institute of Oceanography, Ministry of Natural Resources, Beihai, 536003, China.
Buddha Bahadur BasnetCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Zi-Yang LiCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Gen LiCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Mahmoud EmamPhytochemistry and Plant Systematics Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Qi-Hao WuDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Hong WangCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Bin WeiCollege of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid exploration of natural products not only expands chemical diversity but also plays a vital role in drug discovery by identifying bioactive agents (e.g., antibiotics), revealing novel biological mechanisms, and providing new therapeutic opportunities. However, traditional techniques require extensive resources to screen and prioritize bacteria capable of producing valuable compounds from complex environmental samples. Here, we introduce the PSMPA (

Indexed as

16S rRNABiosynthesis gene clustersMaripanthionesNatural productsPSMPA

Identifiers

PMID41280278
PMCPMC12637254

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.