ArticleRSC advances2025
Design and synthesis of novel spirocyclic oxindole based hybrid scaffolds:
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
The isatin derivatives exhibit various pharmacological activities, including antihypertensive, anti-inflammatory, and ACE-inhibitory effects. The synthetic flexibility of isatin makes it valuable for synthesising various heterocycles, including pharmacologically potent spirocyclic derivatives. In this paper, an efficient procedure is employed for the synthesis of novel alkyne-appended spiro[indoline-3,3'-pyrrolizin]-2-one derivatives (6-8) as a potential anti-inflammatory agent predicted by molecular docking
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.