ReviewRSC advances2025
A comprehensive review on the silane-acid reduction of alkenes in organic synthesis.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
1 author.
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Abstract
Target and diversity-oriented synthesis represents a versatile and efficient strategy for constructing structurally complex and privileged scaffolds from readily or commercially accessible starting materials. The combination of reagents indeed plays a pivotal role in organic synthesis, acting as chemical "tools" that enable specific reactions to occur and driving the creation of new molecules. Reagents facilitate organic transformations, including the controlling of reaction pathways and influencing the complex efficiency and selectivity of the synthesis process. This review highlights the combined use of triethylsilane and trifluoroacetic acid as a powerful system for the chemoselective and regioselective ionic hydrogenation of diverse alkenes. The transformation proceeds through protonation, followed by hydride transfer, affording valuable products with high selectivity. Furthermore, this review covers the reduction of heterocyclic skeletons to saturated compounds
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.