Evidence map›Paper›PMID 41280133›Full record

ArticleIBRO neuroscience reports2025

Association of genotypes at single-nucleotide polymorphisms in

Saba Shakoor, Muhammad Latif, Kam-Hong Kam, Ayesha Nasir, Rashid Mehmood, Mehnaz Akhtar, Maryam Akhlaq, Alisha Batool, Meesam Ali, Kasim Sakran Abass and 4 more

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Article in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Saba ShakoorInstitute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan.
Muhammad LatifDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Kam-Hong KamDivision of General Thoracic Surgery, Department of Surgery, Chia-Yi Christian Hospital, Chiayi 600, Taiwan.
Ayesha NasirDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Rashid MehmoodInstitute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan.
Mehnaz AkhtarDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Maryam AkhlaqDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Alisha BatoolDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Meesam AliDepartment of Zoology, Division of Science and Technology, University of Education, Lahore 54700, Pakistan.
Kasim Sakran AbassCollege of Veterinary Medicine, Department of Physiology, Biochemistry and Pharmacology. University of Kirkuk, Kirkuk 36001, Iraq.
Burhan PashaNishter Hospital Medical Unit 1, Multan 60800, Pakistan.
Adil KhanDepartment of Zoology, Bacha Khan University, Charsadda, Khyber Pakhtunkhwa 24420, Pakistan.
Chien-Chin ChenDepartment of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 600, Taiwan.
Furhan IqbalInstitute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Ischemic stroke is a complex pathological condition in which the brain is damaged due to blockage of blood vessel(s) supplying blood to the brain. This study investigates the genotype and allelic frequency at the single-nucleotide polymorphism (SNP) rs8099917 in Methods: A total of 156 clinically confirmed ischemic stroke patients and 156 age and sex matched controls were enrolled from Multan District in Pakistan during September 2024 till February 2025. Tetra-primer amplification refractory mutation system-polymerase chain reaction (T-ARMS PCR) approach was used to determine the genotype at the screened SNPs. Results: Significant associations of polymorphic TT genotype at rs8099917 in Conclusion: Our results indicated that genotypes at the analyzed SNPs were associated with ischemic stroke in the screened Pakistani population.

Indexed as

GSTP1IL-28BIschemic strokeMTHFRTGF-β1TP53

Identifiers

PMID41280133
PMCPMC12639443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.