ArticlebioRxiv : the preprint server for biology2025
Differential usage of two, distinct DNA-binding domains regulates tissue-specific occupancy of the pioneer factor Zelda.
Eliana F Torres-Zelada, Hideyuki Komori, Hsiao-Yun Liu, Elizabeth D Larson, Ally W H Yang, Zoe A Fitzpatrick, Timothy R Hughes, Christine A Rushlow, Cheng-Yu Lee, Melissa M Harrison
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Eliana F Torres-ZeladaDepartment of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-6843-3529 Hsiao-Yun LiuDepartment of Biology, New York University, New York, NY 10003, USA.
Elizabeth D LarsonDepartment of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0003-1973-6387 Ally W H YangDonnelly Centre and Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada.
Zoe A FitzpatrickDepartment of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706.
Timothy R HughesDonnelly Centre and Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada.ORCID 0000-0002-8721-4719 Cheng-Yu LeeLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Division of Genetic Medicine, Department of Internal Medicine and Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0003-2291-1297 Melissa M HarrisonDepartment of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-8228-6836 Funding
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5MGenomic reprogramming in the early embryoR35GM136298 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Melissa Harrison · 2020 to 2026
$2.8MShared mechanisms regulate transcription-factor activity to control cell fate in neural stem cells and the embryoR01NS111647 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI HARRISON, MELISSA, LEE, CHENG-YU · 2019 to 2023
$1.7MPioneer factor activity in transcription and DNA replicationR35GM148241 · NIGMS · NEW YORK UNIVERSITY · PI CHRISTINE A RUSHLOW · 2023 to 2026
$1.6MNIGMS NIH HHS R35 GM136298NIGMS NIH HHS R35 GM148241NIH HHS P40 OD018537NINDS NIH HHS R01 NS111647
6 · The paper itselfAbstract
Pioneer transcription factors act at the top of gene-regulatory networks by promoting accessible chromatin at the
Identifiers
PMID41280094
PMCPMC12632342
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