Evidence map›Paper›PMID 41280074›Full record

ArticlebioRxiv : the preprint server for biology2025

Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of

Ane Korff, Xiaojing Yang, Ozan Ozdemir, Ananya Samanta, Yong-Dong Wang, Tushar Patni, Alfonso J Lavado, Anoop Murthy Kavirayani, Joseph Ochaba, Berit Powers and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Ane KorffDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Xiaojing YangDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Ozan OzdemirDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Ananya SamantaDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Yong-Dong WangDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Tushar PatniDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Alfonso J LavadoCenter for Pediatric Neurological Disease Research, Pediatric Translational Neuroscience Initiative, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Anoop Murthy KavirayaniDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Joseph OchabaIonis Pharmaceuticals, Carlsbad, California, USA.
Berit PowersIonis Pharmaceuticals, Carlsbad, California, USA.
C Frank BennettIonis Pharmaceuticals, Carlsbad, California, USA.
Hong Joo KimDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-9157-1612
J Paul TaylorDepartment of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-5794-0349

Funding

Dynamic RNA-protein assemblies and neurological diseaseR35NS097974 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI TAYLOR, JOSEPH PAUL · 2017 to 2024
$7.2M
Dynamic RNA-Protein Assemblies and Neurological DiseaseR35NS142868 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Joseph Paul Taylor · 2025 to 2026
$1.8M
NINDS NIH HHS R35 NS097974NINDS NIH HHS R35 NS142868
6 · The paper itself

Abstract

Mutations in

Identifiers

PMID41280074
PMCPMC12637667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.