ArticlebioRxiv : the preprint server for biology2025
A switch in arousal circuit architecture shapes sleep across the lifespan.
Milan Szuperak, Mareike Selcho, Katharina Eichler, Patrick D McClanahan, Kenta Asahina, Jeffrey B Rosa, Christopher Fang-Yen, Andreas S Thum, Matthew S Kayser
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Milan SzuperakDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mareike SelchoDepartment of Animal Physiology, Institute of Biology, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.ORCID 0000-0002-6405-2972 Katharina EichlerDepartment of Genetics, Institute of Biology, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Patrick D McClanahanDepartment of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA 19104.
Kenta AsahinaMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037.ORCID 0000-0001-6359-4369 Jeffrey B RosaDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Christopher Fang-YenDepartment of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia PA 19104.
Andreas S ThumDepartment of Genetics, Institute of Biology, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.ORCID 0000-0002-3830-6596 Matthew S KayserDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-2359-4967 Funding
Dissemination of FlyWire, A Whole-Brain Connectomics ResourceU24NS126935 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2022 to 2026
$5.6MGenetic factors controlling the intensity of social behaviorR35GM119844 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ASAHINA, KENTA · 2016 to 2025
$5.1MCrowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3MInvestigating sleep regulation and function during early developmentR35NS137329 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MATTHEW S KAYSER · 2024 to 2026
$2.6MBuilding brains in our sleep: A Drosophila larval platform for examining sleep and neurogenesisDP2NS111996 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KAYSER, MATTHEW S · 2018 to 2018
$2.4MNIGMS NIH HHS R35 GM119844NIMH NIH HHS RF1 MH117815NINDS NIH HHS DP2 NS111996NINDS NIH HHS R35 NS137329NINDS NIH HHS U24 NS126935
6 · The paper itselfAbstract
Sleep is a continuous behavior across the lifespan, yet its features and functions evolve markedly with development
Identifiers
PMID41280012
PMCPMC12637689
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390