Evidence map›Paper›PMID 41279875›Full record

ArticlebioRxiv : the preprint server for biology2025

Chronic alcohol intake elicits distinct multi-omic profiles in the liver

Craig R G Willis, Muni Swamy Ganjayi, Austin M Brown, Samantha E Moser, Nathaniel J Szewczyk, Brian C Clark, Cory W Baumann

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Craig R G WillisResearch Software and Analytics, University of Exeter, Exeter, UK.
Muni Swamy GanjayiDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.
Austin M BrownDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.
Samantha E MoserHonors Tutorial College, Ohio University, Athens, Ohio, USA.
Nathaniel J SzewczykDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.
Brian C ClarkDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.
Cory W BaumannDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA.

Funding

Neuronal mechanisms involved in aging and ADR01AG067758 · NIA · OHIO UNIVERSITY ATHENS · PI ARNOLD, WILLIAM DAVID, CLARK, BRIAN C · 2021 to 2025
$4.1M
Neural mechanisms of dynapeniaR01AG044424 · NIA · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C · 2014 to 2018
$1.4M
NIA NIH HHS R01 AG044424NIA NIH HHS R01 AG067758
6 · The paper itself

Abstract

Alcohol-related liver disease and alcohol-related myopathy are widespread consequences of chronic alcohol use. However, understanding of the associated molecular mechanisms and effective treatments remains limited. To address this, we employed multi-omics to uncover molecular blueprints of liver

Indexed as

alcohollipidomicslivermetabolomicsmulti-omicsproteomicsskeletal muscletranscriptomics

Identifiers

PMID41279875
PMCPMC12632299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.