Evidence map›Paper›PMID 41279841›Full record

ArticlebioRxiv : the preprint server for biology2025

Ribosomal protection as a linezolid resistance mechanism in

Tobias Funck, Kerry McGowen, Mark R Sullivan, Samuel Zinga, Ian D Wolf, Dennis Nurjadi, Claudia M Denkinger, Eric J Rubin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Tobias FunckDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0009-0003-8660-7451
Kerry McGowenDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0002-8451-4070
Mark R SullivanDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0001-5765-0459
Samuel ZingaDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Ian D WolfDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
Dennis NurjadiInstitute of Medical Microbiology, University of Lübeck & University Hospital Schleswig-Holstein Campus Lübeck, Lübeck, Germany.
Claudia M DenkingerDepartment of Infectious Disease and Tropical Medicine, Heidelberg University Hospital & German Center of Infection Research partner site, Heidelberg, Germany.ORCID 0000-0002-7216-7067
Eric J RubinDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.ORCID 0000-0001-5120-962X

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Molecular, Cellular, and Developmental MechanismsT32GM145407 · NIGMS · HARVARD MEDICAL SCHOOL · PI David L. Van Vactor · 2022 to 2026
$5.2M
Molecular mechanisms of inherent drug resistance in non-tuberculous mycobacteriaR01AI179642 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Jeremy Michael Rock, Eric J. Rubin · 2023 to 2026
$3.1M
Investigating the mechanism of ClpX-mediated degradation in mycobacteriaF30AI188797 · NIAID · HARVARD MEDICAL SCHOOL · PI Samuel Zinga · 2025 to 2026
$98k
NIAID NIH HHS F30 AI188797NIAID NIH HHS R01 AI179642NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273NIGMS NIH HHS T32 GM145407
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41279841
PMCPMC12633451

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.