Evidence map›Paper›PMID 41279783›Full record

ArticlebioRxiv : the preprint server for biology2025

The Christchurch point mutation in mouse APOE reduces Aβ-induced tau and α-synuclein pathologies.

Carlos M Soto-Faguás, Abigail O'Niel, Paul A Mueller, Paula Sanchez-Molina, Randy L Woltjer, Jacob Raber, Vivek K Unni

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos M Soto-FaguásDepartment of Neurology Oregon Health & Science University, Portland, OR, USA.
Abigail O'NielDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA.
Paul A MuellerCenter for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.
Paula Sanchez-MolinaIndependent Researcher, Portland, OR, USA.
Randy L WoltjerDepartment of Pathology and Laboratory Medicine, Oregon Health & Science University, Portland, OR, USA.
Jacob RaberDepartment of Neurology Oregon Health & Science University, Portland, OR, USA.
Vivek K UnniDepartment of Neurology Oregon Health & Science University, Portland, OR, USA.

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
NIA NIH HHS P30 AG066518
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41279783
PMCPMC12637681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.