ArticlebioRxiv : the preprint server for biology2025
EGR1 Mediates Riluzole-Induced Apoptosis in Osteosarcoma via the Yap/p73-Bax Signaling Axis.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
10 authors.
Funding
Abstract
Osteosarcoma (OS), although rare, is the most common primary bone cancer, primarily affecting individuals aged 10-30 years. Despite therapeutic advances, survival rates have remained stagnant for decades. Recent studies show that Riluzole, a glutamate receptor antagonist, induces apoptosis in OS cells both
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Registered trials
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