Evidence map›Paper›PMID 41279677›Full record

ArticlebioRxiv : the preprint server for biology2025

An empirical long-term competition among natural yeast isolates reveals that short-term fitness largely but not entirely predicts long-term outcomes.

Alexandra N Khristich, Olivia M Ghosh, Jean Cc Vila, Shaili Mathur, Abhishek Dutta, Marion Garin, Joseph Schacherer, Dmitri A Petrov

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra N KhristichDepartment of Biology, Stanford University, Stanford CA 94305, USA.ORCID 0000-0002-9240-5720
Olivia M GhoshDepartment of Biology, Stanford University, Stanford CA 94305, USA.ORCID 0000-0003-4149-840X
Jean Cc VilaDepartment of Biology, Stanford University, Stanford CA 94305, USA.ORCID 0000-0003-0499-0200
Shaili MathurDepartment of Biology, Stanford University, Stanford CA 94305, USA.ORCID 0009-0008-3438-4897
Abhishek DuttaUniversité de Strasbourg, CNRS, GMGM UMR 7156, Strasbourg, France.ORCID 0000-0003-2256-6956
Marion GarinUniversité de Strasbourg, CNRS, GMGM UMR 7156, Strasbourg, France.ORCID 0009-0004-9034-5981
Joseph SchachererUniversité de Strasbourg, CNRS, GMGM UMR 7156, Strasbourg, France.ORCID 0000-0002-6606-6884
Dmitri A PetrovDepartment of Biology, Stanford University, Stanford CA 94305, USA.ORCID 0000-0002-3664-9130

Funding

Genomics of rapid adaptation in the lab and in the wildR35GM118165 · NIGMS · STANFORD UNIVERSITY · PI Dmitri Petrov · 2016 to 2026
$8.3M
Understanding the mechanism of diversity generation through directional selectionF32GM149046 · NIGMS · STANFORD UNIVERSITY · PI KHRISTICH, ALEXANDRA · 2023 to 2024
$151k
NIGMS NIH HHS F32 GM149046NIGMS NIH HHS R35 GM118165
6 · The paper itself

Abstract

In this study, we investigate the relative contribution of initial fitness to the long-term success of a genotype competing in a naturally diverse population. Specifically, we compete over 300 genetically barcoded

Identifiers

PMID41279677
PMCPMC12632622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.